The Journal of the Japanese Society of Clinical Cytology
Online ISSN : 1882-7233
Print ISSN : 0387-1193
ISSN-L : 0387-1193
Sertoli-Leydig cell tumor with a matured teratoma of the ovary-A case report
Harumi KOMODAShigeki NUNOKAWAIsao MATSUDAMasafumi UENAKAChiaki KUMAGAISachio INOUETakuya IWASAKIShunichi SASOU
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1987 Volume 26 Issue 1 Pages 124-128

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Abstract

We report a case of Sertoli-Leydig cell tumor (SLCT) with a dermoid cyst in a 53-year-old-Japanese housewife. Hypertrichosis was noticed in the face and legs, but laboratory examination was unremarkable including hormone activities in the blood and urine. Left ovarial tumor was a relatively solid, which was histologically poorly differentiated Sertoli-Leydig cell tumor, and one ovoid cyst, which was a matured teratoma with skin appendages, thyroid tissue and cartilage in its wall.
Imprint smears obtained from a cut-surface of the tumor showed atypical cells having oval nuclei with coarse or fine chromatin and prominent nucleoli, and scanty cyanophilic cytoplasm. In addition, atypical cells having large and round nuclei, and plenty cytoplasm with many vacuoles were observed. Those seemed to be the cells of Leydig cell differentiation. The presence of those cells is important to diagnose SLCT in imprint cytology of the ovarial tumor.

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© The Japanese Society of Clinical Cytology
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