The Journal of the Japanese Society of Clinical Cytology
Online ISSN : 1882-7233
Print ISSN : 0387-1193
ISSN-L : 0387-1193
A cytological study on two cases of meningioma with chest metastasis
Hitoshi HARAKoichi SUDAMasahiro KIMURAEri ISHIIKazuhiko TAKASOTetsuo WAKAOHiroshi YOKOYAMA
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1987 Volume 26 Issue 6 Pages 1072-1075

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Abstract
The cytological characteristics of tumor cells obtained from two cases of tumors of meningeal origin with extracranial metastasis are presented. The first case was meningothelial meningioma, Grade I with pulmonary metastasis. The primary focus showed the histologically typical whorl arrangement and the presence of psammoma bodies in the proliferating center of the tumor cells. Cytologically the nuclei of these tumor cells were devoid of all characteristics of malignancy. The second case was meningothelial meningioma, Grade m with extra-cranial metastasis to the chest. Cytologically these tumor cells were polyhedral or spindle shaped, rich in cytoplasm and the nucleo-cytoplasmic ratio was not very high, however the nuclei and nucleoli were rather large, suggestive of malignant non-epithelial tumor. This case had repeated local recurrences and generalized metastasis occurred at the final stage.
These two cases were similar meningothelial meningiomas with chest metastasis, however there were differences in their clinical course and cytological findings.
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© The Japanese Society of Clinical Cytology
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