A case report of primary squamous cell carcinoma of the left breast during lactation

Abstract

A rare case of primary squamous cell carcinoma of the left breast was reported.
A lactating 28-year-old female presented with chief complaint of “a lump in the left breast.” Needle aspiration yielded scattered tumor cells which were elongated, tadpoleand oval-shaped with deeply eosinophilic or light green cytoplasm against a background of necrotic debris and inflammatory cells. The tumor cells exhibited cytoplasmic keratinization and were arranged in cannibalistic patterns. These findings are the routine diagnostic features of squamous cell carcinoma.
An intraoperative imprint smear contained only a bery few carcinoma cells which resembled ductal carcinoma cells, i.e., were clustered, had foamy cytoplasm, a granular chromatin pattern, and prominent nucleoli in addition to squamous carcinoma cells. The resected tumor measured 3.5×3.0 cm in diameter, and featured a cyst within the tumor, 2.5×1.5 cm in diameter in its central area. The histopathological diagonosis was primary squamous cell carcinoma of the breast.