1991 Volume 30 Issue 6 Pages 1130-1135
The cytological features of two cases of pulmonary sclerosing hemangioma were studied by examining smears obtained by fine needle biopsy and aspiration.The cytological characteristics of these sclerosing hemangioma were as follows: 1) Small round cells were dispersed or arranged in papillary patterns. 2) Large polygonal cells, which had a large amount of cytoplasm, a large nucleus and significant numbers of nucleoli, were dispersed. 3) Small cells, which had a smaller nucleus and clear cytoplasm, were present. 4) Spindle-shaped nuclei were noted in a papillary arrangment. 5) Many histiocytes, containing hemosiderin were scattered among the cellular clusters. 6) Inflammatory cells were found.
For immunoperoxidase staining, cytological specimens were stained with PE-10, and paraffin-embedded tissue sections were stained with PE-10, keratin and EMA.Small round cells and large polygonal cells showed immunoreactivity with PE-10 and keratin.Therefore we thought those cells might be epithelial and of pneumocytic origin.
The valuable features in differential diagnosis are the presence of numerous cell types, spindle-shaped nuclei, hemosiderinladen histiocytes, bloody background, etc.
In conclusion, we believe it is possible to make a preoperative diagnosis of pulmonary sclerosing hemangioma from clinical findings and the above features.
