1994 Volume 33 Issue 6 Pages 1150-1154
We report a case of primary soft tissue lymphoma.The patient was a 75-year-old woman who complained of pain and swelling in her right leg.The tibialis anterior muscle was replaced by yellowish soft tumor, and a frozen section revealed diffuse proliferation of atypical cells with occasional lipid droplets. Imprint cytology showed scattered neoplastic cells with round, sometimes cleaved nuclei containing one or several nucleoli.The cytoplasm was scarit, but small numbers of tiny lipid droplets were seen. Pathologically, round-cell type liposarcoma was suspected at first, but immunohistochemical positivity for LCA and L-26 demonstrated the tumor to be a genuine lymphoma.No dissemination was discovered upon examination by palpation, radiography, CT scans, MRI, and gailium scintigraphy. Systemic chemotherapy was performed, and no evidence of disease has been detected for nearly three years.Cytological and immunohistochemical studies appear to be potential diagnostic tools for primary soft tissue lymphoma.
