Abstract
Background: Papillary squamous cell carcinoma (PSCC) and adenoid basal carcinoma (ABC) of the uterine cervix are rare tumors. This report describes an extremely rare case of PSCC concomitant with ABC.
Case: The patient was a 71-year-old Japanese woman who was found to have abnormal cervical cytology results. Such as clusters of squamoid atypical cells, atypical transitional cells and small basaloid cells. After the conization, total abdominal hysterectomy and bilateral salpingooophor-ectomy were performed.
Histologically, in the uterine cervix, the superficial lesion was represented by marked papillary proliferation of several layers of atypical cells resembling to non-keratinized squamous cell carcinoma and transitional cell carcinoma of the urinary tract (histological feature of PSCC). The deep lesion consisted of nests of basaloid cells with focal glandular or squamoid patterns (histological feature of ABC).
Conclusion: This report described an extremely rare case of PSCC concomitant with ABC. In this case, there were two histological features (PSCC and ABC) in close association with one another at the uterine cervix. We suspect that the histogenesis of this case is (1) coincidental appearance of two cancers (double cancer) or (2) differentiation of one cancer (PSCC or ABC) to the other.
