1999 Volume 38 Issue 4 Pages 358-362
Background: Double cancer in female genital organs is very rare, and preoperative diagnosis is very difficult. Coexistence with clear cell adenocarcinoma of the ovary and adenocarcinoma in situ of the cervix is also rare. It is possible to diagnose double cancer by cytological findings of a cervical smear.
Case: The patient was a 37-year-old woman whose abdominal CT scan revealed an irregular shaped solid mass in the cystic right ovary. The characteristic findings of the cervical cytology were as follows: 1. Two types of malignant cells were found. One from clear cell adenocarcinoma, the other from cervical adenocarcinoma in situ. 2. One showed clusters with enlarged nuclei, prominent nucleoli, a distinct cell border, collagenous stroma within the cell ball on a clean background. 3. The other showed aggregated atypical glandular cells, enlarged nuclei with protrusions from the cytoplasm, and fine granular chromatin. The histological postoperative diagnosis was clear cell adenocarcinoma of the ovary and adenocarcinoma in situ of the cervix.
Conclusion: It is possible diagnose coexistent clear cell adenocarcinoma of the ovary and adenocarcinoma in situ of the cervix by cytological findings of a cervical smear.
