A case of angiosarcoma arising from frontal scalp

Abstract

We report a case of angiosarcoma arising from the frontal scalp in an 82-year-old woman. Imprint cytology from a metastatic lung tumor showed that most tumor cells were spindle or polygonal, and were arranged in a trabecular pattern. Some tumor cells contained hemosiderin granules in the cytoplasm, and severe hemorrhage occurred in the background, consistent with the cytological features of angiosarcoma. Furthermore, immunocytochemical examination revealed that the tumor cells were positive for vimentin, Factor VIII-relating antigen, and CD 34. These results sugges that a cytological approach including immunocytochemistry is potentially useful to establish a precise diagnosis of angiosarcoma.