1999 Volume 38 Issue 6 Pages 504-510
Objective: We studied the cytological features of myxoid liposarcoma (MLPS). round cell liposarcoma (RCLPS) and mixed myxoid and round cell liposarcoma (M/RCLPS), Study Design:Cytological findings and cell measurements of FNA or imprint materials from MLPS (7 cases), M/RCLPS (3 cases) and RCLPS (2 cases) were investigated. We studied the nuclear shape, background myxoid substance, appearance of atypical lipoblasts, and presence of capillary vessels on cytological materials. The nuclear area and major/minor axis ratio of nuclei of cells were estimated.
Results: Tear-drop shaped nuclei were only observed in MLPS. Atypical lipoblasts were often seen in all types of liposarcoma, and background myxoid substance was seen in every type except RCLPS, but fragmented capillary vessels were not commonly observed on cytological materials. Nuclear area was significantly larger in liposarcomas with a round cell element than in MLPS, whereas the major/minor axis ratio of nuclei was significantly larger in MLPS.
Conclusion: MLPS shows characteristic cytological features, and our results suggest that it is possible to make a cytological diagnosis of MLPS.
