The Journal of the Japanese Society of Clinical Cytology
Online ISSN : 1882-7233
Print ISSN : 0387-1193
ISSN-L : 0387-1193
Eosinophilic granuloma of the bone
Cytologic feature of eosinophils
Shingo WAKATSUKIMitsuyoshi HIROKAWATakuo KANAHARAMiki YAMAGUCHIChikako TAKAIJunko YAMADAToshiaki SANO
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2000 Volume 39 Issue 3 Pages 213-218

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Abstract
Background: Many studies of the morphology of Langerhans cells in eosinophilic granuloma have been reported, but there have been no reports describing the morphology of eosinophils in detail.
Case: A one-year-old female presented with a solid mass in the right pterygopalatine fossa, measuring 4×4×3 cm. H & E-stained imprint cytology specimen revealed Langerhans cell and eosinophils that showed hypersegmentation and indistinct eosinophilic granules. Three and more segmentation was observed in 61% of eosinophils. The lobe index was 2.7.
Conclusion: Since eosinophils seen in eosinophilic granuloma show hypersegmentation and indistinct eosinophilic granules, we may mistake them for neutrophils in Papanicolaou-stained smears. When this disease is suspected, Giemsa-stained smears should be used.
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© The Japanese Society of Clinical Cytology
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