Abstract
A rare case of subependymal giant cell astrocytoma without tuberous sclerosis is documented. A tumor was detected in the anterior horn of the left lateral ventricle of a 12-year-old boy. Both imprint smear cytology and histology revealed the presence of large epithelioid cells with eccentric nuclei and thick eosinophilic cytoplasm. Most epithelioid cells were strongly positive for S-100, vimentin, and neuron specific enolase on immunohistochemistry, and a few cells showed weak a positivity for glial fibrillary acidic protein and neurofilament. These large epithelioid cells were considered to represent an intermediate lineage between astrocytes and neurons.
