A case of neuroendocrine carcinoma with HPV-18 infection arising in the uterine cervix

Abstract

We report a case of neuroendocrine carcinoma of the uterine cervix with HPV-18infcction in a 145-year-old wolnan.
The tulllor arose in the uterine cervix. with the tumor surface necrotic and bioody. Cytology showed abundant tumor cell ina Ilecrotic background, with slnall rourld or short spindle nuclei, scant cytoplasnl or strippcd nuclei, scattered individually and aggregated in small clusters, and delicate or coars cgranular cllrolnatin.
Hislologically, small turnor cell swere arranged in nests cell cords and a ribbonpattern.Thistumor wasdiagnosedasby spellout (ISH) a sneuroendocrinecarcillomawitll HPV-18illfectiollarisingintheuterinecervix. We fouu/d cytological examination to be useful in this diagrlosis.