Journal of the Japan Society of Cranio-Maxillo-Facial Surgery
Online ISSN : 2433-7838
Print ISSN : 0914-594X
Case Report
A Case of Recurrent Squamoid Eccrine Ductal Carcinoma Responding to an Immune Checkpoint Inhibitor
Shinichi INOUE
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2023 Volume 39 Issue 3 Pages 74-80

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Abstract

  Squamoid eccrine ductal carcinoma (SEDC) is a subtype of squamous cell carcinoma. It is a malignant tumor composed of squamous cell carcinoma and adenocarcinoma. The first three reported cases of SEDC were described in 1997 by Wong et al. Superficial diagnostic biopsies often lead to the misdiagnosis of SEDC as cutaneous cell carcinoma. Herein, we report a rare case of SEDC with repeated local recurrence following resection that was resolved with drug therapy. In our patient, SEDC was unresectable after the fifth recurrence; however, the tumor disappeared after combination treatment with chemotherapy and an immune checkpoint inhibitor. Herein, we present the case along with relevant literature.

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© 2023 Japan Society of Cranio-Maxillo-Facial Surgery
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