2017 Volume 38 Issue 2 Pages 192-197
Coffin-Lowry syndrome （CLS） is an X-linked recessive disease, causing malformations characterized by typical facial features, short stature, frame deformity and severe intellectual disability. Findings in the oral cavity associated with CLS include premature exfoliation of primary teeth without root resorption, early tooth loss due to short root, and periodontal disease. There appear to be no reports about periodontal treatment for such cases.
We report the periodontal treatment of two cases：a 28-year-old and a 46-year-old. At the first visit, we found a lot of dental plaque and calculus, poor oral hygiene state, reddening and swelling of the gingiva, and deep periodontal pockets. We also found tooth mobility and alveolar resorption in both cases.
Because of severe intellectual disability, we performed oral hygiene through mouth cleaning with assistance care and professional care. We provided non-surgical periodontal therapy while applying behavior management. After a re-evaluation, we performed a combination of antibacterial therapy, scaling and root planing for the deep periodontal pockets. When necessary, we used intravenous sedation for periodontal treatment of the patients.
After these treatments, the state of the periodontal tissue was improved so we carried out supportive periodontal therapy.
Coffin-Lowry syndrome related to periodontitis due to genetic disorder accompanied the clinical findings of these two cases. In addition, we think that it is important to perform oral management from an early stage, as well as after periodontal treatment.
