A Case of Lung Cancer with Trousseau’s Syndrome Triggered by Bilateral Toe Ulcers

Abstract

 Trousseau’s syndrome is a condition caused by a hypercoagulable state associated with malignant tumors, leading to systemic thromboembolic events. It is characterized by cancer-associated thrombosis, including disseminated intravascular coagulation, in patients with malignancies（particularly adenocarcinomas）; and systemic embolism, most notably cerebral infarction, resulting from nonbacterial thrombotic endocarditis. It is often difficult to treat and has a poor prognosis. We report a case of Trousseau’s syndrome that was diagnosed following the onset of toe ulcers as the initial manifestation, with lung cancer, deep vein thrombosis, and cerebral infarction subsequently identified. Our findings suggest the necessity of including Trousseau’s syndrome as a differential diagnosis for departments managing toe ulcers.