A clinical study of seven cases of malignant tumors metastatic to the mandibular bone

Abstract

This study examined the clinical findings, treatment and outcome of seven patients with mandibular bone metastatic tumors. The most common location of the metastatic lesion was the molar region of the jaws. The primary tumors in these patients included papillary carcinoma and follicular carcinoma of the thyroid gland, osteosarcoma of the tibia, neuroepithelioma of the lumbar dura, hepatocellular carcinoma of the liver, adenocarcinoma of the rectum, and small cell carcinoma of the lung. The most common symptoms were pain of the mandible and paresthesia of the mental nerve. When primary tumors and generalized metastasis were uncontrolled, the patients died within six months. When the primary tumors and generalized metastasis were controlled, we treated them aggressively. One patient survived seven year and two months after treatment, and now two patients are still alive more than three years after treatment.