Effectiveness of injection of minocycline solution on salivary fistula and sialocele after parotid surgery

Abstract

Salivary fistula and sialocele are rare diseases that occur especially after parotid surgery. They can be generally treated with local oppression and/or drainage; however, they show a delay in healing occasionally. We herein report four cases where local injection of a minocycline hydrochloric acid solution was effective for persistent diseases after parotid surgery. There no severe complications, including facial nerve paralysis, were observed in this therapy. Minocycline has been used as a sclerotherapy for chylous fistula following neck dissection, renal cyst, etc. Therefore, our minocycline procedure may be considered as the initial treatment modality for patients suffering from prolonged salivary fistula or sialocele after parotid surgery.