Abstract
Primary liposarcoma of the thyroid gland is extremely rare with only seven cases reported in English literature. We report a rare case of liposarcoma of the thyroid gland. The patient was a 76-year-old woman who came to our hospital complaining of swelling on the right side of her neck. The ultrasound and CT of the neck described the extension of a tumor to the left lobe from the right lobe of the thyroid. A total thyroidectomy was performed for the tumor resection. After the surgery, a well-differentiated liposarcoma of the thyroid was certified histopathologically. External radiotherapy was required for additional treatment due to a poor margin. In spite of the combination therapy, both surgery and radiotherapy, a metastatic tumor occurred in the anterior mediastinum 9 months after the primary treatment. Surgical resection was chosen for further treatment. No recurrent signs appeared on the follow up 13 months later.