Maxillary sinus squamous cell carcinomas

Abstract

We report a retrospective study of 19 maxillary sinus squamous cell carcinoma patients treated in Kyoto Prefectural University of Medicine from April 2005 to March 2012. We examined the treatment results and the sites of recurrence, and evaluated the histopathological effect of intra-arterial chemo-radiotherapy, with which T3 or T4 cases were treated, and checked the relationship between the histopathological effect and the prognosis. The 5-year disease-specific survival rate was 68.4% for all cases, and 75% for T3 and T4a cases in particular. There were nine cases with recurrence of disease, and four cases suffered from recurrence of the primary tumor. The local control and the prognosis were dependent on the histopathological effect of intra-arterial chemo-radiotherapy. The treatment with combination of intra-arterial chemo-radiotherapy and surgery for maxillary sinus squamous cell carcinoma gives satisfactory results in terms of local control and survival rate.