Abstract
We performed adjuvant chemotherapy with S-1 for advanced head and neck squamous cell carcinoma after radical treatment. To evaluate the efficacy of our adjuvant chemotherapy with S-1, we retrospectively analyzed 91 patients in our institute between 2006 and 2009. We reviewed survival rate, recurrence rate and distant recurrence rate in the S-1 group and the non S-1 group. The 3-year survival rates were 73% in the S-1 group and 57% in the non S-1 group. The 3-year recurrence rate was 38% in the S-1 group and 49% in the non S-1 group. The 3-year distant recurrence rate was 14% in the S-1 group and 22% in the non S-1 group. These rates were not significantly different but showed a good tendency, so we consider that adjuvant chemotherapy with S-1 is an effective treatment.
