Abstract
Warthin's tumor is the second most common benign parotid gland tumor next to pleomorphic adenoma. In addition, malignant transformation of Warthin's tumor is extremely rare. We report a rare case of salivary duct carcinoma arising in Warthin's tumor of the right parotid gland in a 66-year-old male. The patient had been aware of a mass in the bottom right ear for a few years. In addition, he was also aware of right cervical lymphadenopathy, and it rapidly increased. Aspiration cytology in the right parotid gland tumor showed Papanicolaou Class V (carcinoma). We performed a total parotidectomy and neck dissection. The removed tumor was in contact with two well encapsulated nodular lesions (about 10 mm each) and histopathological findings showed Warthin's tumor and poorly differentiated salivary duct carcinoma. The patient was carefully followed up after postoperative chemoradiotherapy. 12 months later, he had a recurrence in the left cervical lymph node and distant metastasis in the stomach and died 20 months later.
