A case of intestinal-type adenocarcinoma treated with skull base surgery after induction chemotherapy

Abstract

Intestinal-type adenocarcinoma is a rare malignant tumor of the nasal cavity and paranasal sinus. We describe a case of intestinal-type adenocarcinoma of the ethmoid sinus in a 58-year-old man. He had no history of wood dust inhalation. CT and MRI demonstrated a mass that extended from the ethmoid sinus to the anterior skull base. First, we performed induction chemotherapy using cisplatin （CDDP）, 5-FU and leucovorin （LV）. After that, we performed anterior craniofacial resection of the tumor, and postoperative radiotherapy.
The patient survives without recurrence 6 months after the operation.