Abstract
We present a case of noninvasive paranasal aspergillosis with brain abscess during postoperative follow-up of endoscopic sinus surgery. The patient was treated with voriconazole. A 74-year-old woman underwent endoscopic sinus surgery with diagnosis of right orbital syndrome due to paranasal fungal disease. The diagnosis was noninvasive paranasal aspergillosis. Seven months after surgery, image findings showed thickening around the right orbital tip and dura, and brain abscess. Long-term treatment with voriconazole was performed due to invasive paranasal aspergillosis. The brain abscess improved at 9 months. Even if invasive paranasal aspergillosis cannot be confirmed in pathological findings in patients with impaired immune function, if invasive paranasal aspergillosis is suspected from progress, examination findings, images, etc., close observation with images and aggressive treatment by antifungal agent seem to be necessary.
