A retrospective study on T2N0 laryngeal cancer

Abstract

We retrospectively analyzed 42 patients with T2N0 laryngeal squamous cell carcinoma treated in our hospital between 2002 and 2017. There were 39 males and 3 females ranging in age from 49 to 89 years old with the median age of 68. Among the 42 patients, 6（14.3％）patients, 32（76.2％）patients and 4（9.5％）patients were classified into supraglottic, glottic and subglottic, respectively. Among the 32 glottic cancer patients, there were 20（62.5％）patients with anterior commissure invasion and 12（37.5％）patients without it. The overall and disease-specific survival rates were 95.2％ and 97.6％, respectively. The 3-year laryngeal preservation rate of all 42 patients was 76.2％. The 3-year laryngeal preservation rate was 69.0％ in the 29 patients who received radiation therapy alone, and 92.3％ in the 13 patients who received chemoradiotherapy. There was no significant difference between the radiation-alone group and the chemoradiation group. A clinical trial is needed to assess the effects of chemoradiotherapy on T2N0 laryngeal squamous cell carcinoma.