A clinical study of 22 cases of submandibular gland carcinoma

Abstract

A clinical study was made of 22 patients with previously untreated submandibular gland carcinomas in our department between 2009 and 2018. Overall three- and five-year survival rates were both 79.4％ and relapse-free three- and five-year survival rates were both 69.8％. All of the cases of recurrence showed distant metastasis.
Six patients had distant metastasis, four patients died of the disease, and two patients were alive with recurrence. Multivariate analysis showed lymph node metastasis was a significant factor for relapse-free survival. Our study suggested that death due to submandibular gland carcinoma occurred mainly due to distant metastasis. New medical treatments need to be developed to improve survival in patients with submandibular gland carcinoma.