Abstract
Carcinoma rarely originates in thyroglossal duct cysts. We report a case of papillary carcinoma that originated in a thyroglossal duct cyst. A 42-year-old woman presented with a 5-year history of a slow-growing left-sided anterior neck mass. Physical examination showed a palpable mobile mass with a maximum diameter of 20mm. Ultrasonography revealed fibrous bands extending from the head and tail of the mass, and these fibrous bands were continuous with the hyoid bone and the pyramidal lobe, respectively. Fine-needle aspiration cytology of the mass revealed papillary carcinoma. Thyroid cancer and metastasis were excluded; therefore, we performed the Sistrunk procedure for resection of the tumor together with a central portion of the hyoid bone. Postoperative histopathological examination confirmed papillary carcinoma with negative surgical margin and pre-laryngeal lymph node metastasis. No recurrence was observed at the 12-month postoperative follow-up.