Abstract
We report a retrospective study of 8 oral tongue cancer patients treated in Kyoto Prefectural University of Medicine from April 2017 to November 2019. Inclusion criteria were as follows: primary tumor, more than 2cm in greatest dimension, deeper than 10mm, resected after neo-adjuvant chemotherapy （NAC）, PCE therapy. We evaluated the efficacy and adverse events for NAC and observed the extent of the residual tumor in the permanent section and analyzed the resection line. The completion rate of treatment was 87.5% and 7 cases avoided reconstruction with myocutaneous flap; all the cases underwent the resection with negative margins. From the comparison between the diameter on MRI and in the specimen, the true diameter could be the extent of the tumor on MRI after NAC. When the tumors became fragmented, characteristically they showed a faint contrast, but could not be identified on ADC-map. As a result, it was shown that in limited surgery after NAC, the true range of the tumor could be that on the MRI image after NAC.
