The study of necessity and therapeutic effect of gastrostomy nutrition in concurrent chemoradiation with cisplatin

Abstract

A total of 49 patients with head and neck cancer treated with concurrent chemoradiation with cisplatin （CDDP） in our department between April 2013 and December 2017 were studied retrospectively to determine the necessity and therapeutic effect of gastrostomy nutrition. Gastrostomy nutrition was used in a total of 30 patients; usage was lower in patients with laryngeal cancer than in those with pharyngeal cancer. Gastrostomy nutrition did not correlate significantly with the disease-free survival, overall survival, or cumulative cisplatin dose. Patients who received prophylactic irradiation to the entire neck were less likely to use gastrostomy nutrition than those who received definitive irradiation to neck lymph node metastasis. The use of gastrostomy nutrition was more common in patients with a pre-treatment weight of less than 64kg, in whom gastrostomy nutrition tended to prevent weight loss during treatment.