Abstract
We report a rare case of persistent thyrotoxicosis with destructive thyroiditis with a huge adenomatous goiter cured by thyroidectomy. A 56-year-old male patient with acute heart failure and thyrotoxicosis was referred to our hospital for a detailed examination of thyrotoxicosis. The examination revealed destructive thyroiditis with a huge adenomatous goiter. Because his serum FT3 and FT4 levels had not decreased for three months after conservative treatment, a thyroidectomy was performed. Thereafter, his serum FT3 and FT4 levels normalized, and the thyrotoxicosis improved. A thyroidectomy should be considered for persistent thyrotoxicosis that is refractory to conservative treatment.