Abstract
We encountered a case of carotid blowout syndrome (CBS) as a complication of postoperative adjuvant chemoradiotherapy for advanced tongue cancer. The patient, a 56-year-old male, underwent primary tumor resection, followed by postoperative adjuvant chemoradiotherapy for tongue cancer (cT4aN3bM0). One month after treatment completion, he developed mandibular osteomyelitis, followed by CBS two months later. Emergency endovascular treatment, including internal carotid artery stent graft placement and embolization of the external carotid artery, successfully achieved hemostasis. CBS is a severe complication associated with head and neck cancer treatment and can be fatal without prompt diagnosis and intervention. Recently, endovascular treatment has been used occasionally as a primary treatment option. Determining the appropriate indications for endovascular treatment is crucial for treatment selection.