JOURNAL OF JAPAN SOCIETY FOR HEAD AND NECK SURGERY
Online ISSN : 1884-474X
Print ISSN : 1349-581X
ISSN-L : 1349-581X
Results of Antithyroid Drugs and Indication for Surgery in Basedow's Disease
Hiroyuki YamadaRyoji IshidaSatoshi NakamuraTomohito FukeToshifumi Tomioka
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2006 Volume 16 Issue 1 Pages 83-89

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Abstract
Sixty-one patients with Basedow's disease except for 1 untreated patient were administered antithyroid drugs by our procedures. Seventeen patients that were well controlled were compared with 12 patients that experienced recurrence after the therapy. Patients under 40 years old when an anti thyroid drug therapy is started; patients whose TSH receptor antibody cannot be changed to nega tive, and patients that cannot receive MMI should be positively considered as to indication for surgery. In 45 patients who received surgery for Basedow's disease, postoperative thyroid functions were within the normal range in 25 patients. Postoperative hypothyroidism was observed in 19 patients, and recurrence was observed in only one patient. Postoperative recurrence should be avoided, and postoperative hypothyroidism should be considered acceptable. Understanding regarding post operative hypothyroidism is necessary in patients who are considered for surgery.
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