Abstract
We applied a new bilayer artificial mucous membrane (atelocollagen) to the mucosal defect of 30 patients with cancer of the oral cavity (tongue: 22, oral floor: 3, etc.). The material was found to be easy to handle, adhere well and promote hemostasis, relieve pain, limit infection, and promote rapid epithelization with minimum contraction. The results suggest the safety and effectiveness of the ma-terial for clinical use. Key words: artificial mucous membrane, cancer of the oral cavity, atelocollagen, tongue cancer