Abstract
Two cases of juvenile laryngeal papilloma were treated by laser surgery and α-interferon (αIFN). In the case of multiple papilloma, the diffuse papillomatosis of bilateral vocal cords demanded four-time operations although the pedinculated papilloma of the right arytenoid was curable with a single laser surgery. The web of the anterior commissure was formed after operation. The case of the solitary pedinculated of the right vocal cord was curable with a single laser surgery. After the third and fourth operations of the multiple case and the single operation of the solitary type, αIFN was medicated with an ultrasonic nebulizer. This medication was useful without side effects.