Abstract
En-bloc resection of the anterior skull base was performed successfully in 61-year-old female with squamous cell carcinoma of the frontal sinus. The frontal sinus was destryoed completely by the tumor and the tumor infiltrated both to the dura and the forehead-skin. Thorough transcranial and transf acial approach, the cancer was separated from sorrounding tissue with safety margin and removed en-bloc. The skull base was reconstructed using the rectus abdominis muscle flap, which filled the orbit after exenteration of orbit. She is alive NED after 21 months after surgery.