The Journal of Japan Society for Infection and Aerosol in Otorhinolaryngology
Online ISSN : 2434-1932
Print ISSN : 2188-0077
Original Articles
The Effect of Tebipenem-pivoxil (TBPM-PI) in Children with Refractory Otitis Media
Kazuma Sugahara, Yukari Kano, Makoto Hashimoto, Hiroaki Shimogori, Hiroshi Yamashita
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Keywords: refractory otitis media, tebipenem-pivoxil, Streptococcus pneumonia, Haemophilus influenzae
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2014 Volume 2 Issue 1 Pages 19-22

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Abstract

This study aimed to evaluate the efficacy of TBPM-PI in children with refractory otitis media. Sixteen cases of acute otitis media in childhood which were resistant to prior therapy were evaluated. Symptom scores (ear pain, high fever, displeasure) and tympanic membrane scores (rubefaction, swelling, discharge) were evaluated before and after treatment with antimicrobial agents. The cure rate was 87.5%. In addition, TBPM-PI showed favorable antibacterial activities against the isolated pathogens. The results suggest that TBPM-PI is a useful antibiotic in cases of pediatric refractory otitis media.

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© 2014 Japan Society for Infection and Aerosol in Otorhinolaryngology
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