2025 Volume 37 Issue 2 Pages 29-33
A 49-year-old man was being treated for Crohn's disease with intravenous infliximab and oral azathioprine. The patient visited our hospital with chief complaints of headache, a fever, and an inability to remember the date. He had impaired consciousness and symptoms of meningeal irritation and was diagnosed with Listeria monocytogenes meningitis based on cerebrospinal fluid findings. Antibiotic treatment was started, but on day 6 of hospitalization, a decrease in the level of consciousness due to the onset of hydrocephalus was observed. External ventricular drainage was performed, and the patient's symptoms improved. The effectiveness of ventricular drainage during the acute phase of bacterial meningitis has not been established. We herein report a relatively rare case of adult-onset Listeria monocytogenes meningitis in which ventricular drainage was performed and the prognosis was favorable.