Abstract
To elucidate the effects of Change of feeding time period on digestion, changes in food intake, liver glycogen, pancreatic amylase and trypsinogen activities and plasma amylase activity were analyzed in mice.
1) Even after change of feeding time period (9:00-21:00) to (21:00-9:00), food intake was not changed, still 4g/day.
2) Liver glycogen content at 9:00 on the 2nd day after the change already increased from 0mg/g of liver to 50-60mg/g of liver which was almost same with the content at 21:00 before the change.
3) Pancreatic amylase and trypsinogen activities increased significantly at 4th-6th day after the change and then decreased. These activities, however, were higher than the control levels of activities even at 11th day after the change, except amylase in the two weeks traind mice.
4) The temporal increase of pancreatic enzyme activities may be caused by the inhibition of enzyme secretion since plasma amylase activity also was observed to increase a little latter.