Abstract
Plasma cell granuloma (PCG) is a reactive lesion, not a neoplastic lesion, and most commonly develops in the lung. PCG in the oral cavity is rare. We report a case of gingival PCG. The patient was a 65-year-old man who presented complaining of gingival swelling. A raised lesion was seen on the lingual side of the right mandibular first and second molar region, with the surface showing a granular appearance. The lesion was surgically resected and histopathological diagnosis was gingival hyperplasia with inflammatory cell infiltration. The patient stopped going to hospital after treatment. Two years later, he re-visited with gingival pain. A mass lesion at the same location on the right mandible was observed, appearing as an exophytic lobular shaped pedunculated mass. Surgical removal including periosteum was again performed. Histopathologically, the lesion was diagnosed as PCG. Massive plasma cell infiltration was observed, but these plasma cells did not show monoclonality. Postoperative progress was good, and no abnormalities have been seen as of 6 months postoperatively.