Journal of Japanese Society of Oral Medicine
Online ISSN : 2186-6155
Print ISSN : 2186-6147
ISSN-L : 2186-6147
Case Report
Medication-related Osteonecrosis of the Palatal Torus: Report of Two Cases under Zoledronate Administration for Breast Cancer Bone Metastases
Hiroe KAKEHASHIHiromi YAMASHITASeigo OHBAIzumi ASAHINA
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2015 Volume 21 Issue 1 Pages 21-26

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Abstract
Osteonecrosis of the palate associated with antiresorptive medications such as bisphosphonates is rare. We underwent surgical removal of the torus after conservative treatment in 2 cases of osteonecrosis of the palate at different stages, who received intravenous zoledronate for metastatic breast cancer. A stage 3 case had poor prognosis with a remaining fistula, while a stage 1 case healed with complete epithelialization. These results suggest that surgical treatment at early stage might be effective for osteonecrosis of the jaw caused by zoledronate.
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© 2015 Japanese Society of Oral Medicine
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