Two Cases of Verruciform Xanthoma in the Oral Cavity and a Clinco-Statistical Study of Japanese Cases

Abstract

Verruciform xanthoma is an uncommon lesion that is characterized by the proliferation of foamy or xanthoma cells in the submucosal stroma, and is generally considered to be a reactive change, not to a true neoplasm. We report two cases of Verruciform xanthoma in the Oral Cavity and a review of the literature. We describe an 83-year-old woman （Case 1） with an exophytic mass on the right margin of the mandible and a 69-year-old woman （Case 2） with an exophytic pedunculated mass on the tongue. Both lesions were surgically resected and histopathologically diagnosed as Verruciform xanthoma.