Laugier-Hunziker-Baran Syndrome: A Case Report

Abstract

Laugier-Hunziker-Baran syndrome （LHB） is characterized by acquired hyperpigmentation of the oral mucosa, digital skin and nails without gastrointestinal diseases. We experienced a patient who was found to demonstrate disease progression. The patient was a 71-year-old woman with multiple instances of dark-brown hyperpigmentation on her lower lip and buccal mucosa. After four years of observation, dark-brown macules on the digital skin and nails were newly observed. We ultimately diagnosed her with LHB based on the results of systemic examinations. Diagnosis of hyperpigmentation of the oral mucosa requires careful monitoring of the systemic status and strict observations.