Abstract
Metastatic cancer in the oral cavity is relatively rare. An 89-year-old man was hospitalized for lung
adenocarcinoma. The radiological findings revealed multiple metastasis of lung cancer. Before beginning treatment with human anti-RANKL monoclonal antibody to inhibit bone metastasis, the patient was referred to our department for investigation of the oral cavity. The patient underwent extraction of a poor-prognosis premolar. Six months after the extraction, an aggressive large-sized mass with no bone resorption was observed in the maxillary region. Subsequently, a biopsy of the lesion was performed and the resulting histopathological and clinical findings were consistent with lung cancer metastasis into the oral cavity.
