Abstract
Bone metastases are common in patients with prostate cancer, but they are mainly located in the lumbar spine, thoracic spine, and pelvis; metastases to the head and neck region are extremely rare. In this report, we describe a case of mandibular metastasis of prostate cancer in a patient who was referred to our department with a complaint of mandibular swelling. Histopathological examination revealed immunostaining, CK7 and CK20 were negative, PSA, a prostate cancer marker, was partially positive, and p504S, NKX3.1 was strongly positive in the nucleus. For these reasons, he was diagnosed with bone metastasis of prostate cancer.