Abstract
Pregabalin is the first line of treatment for fibromyalgia in adults. However, its use for pediatric patients has yet to be established. We report here two adolescents who were successfully treated for juvenile fibromyalgia (JFM) within a year by the use of pregabalin. A ten-year-old boy complained of pain in the extremities, which had started at seven years of age and continued to worsen to the point of disrupting daily behavior, such as attending school. Six months of pregabalin administration and multimodal treatments restored normalcy. A thirteen-year-old girl complained of pain in the extremities. She had begun to experience such pain at eleven years of age. She received pregabalin and physical therapy. After seven months, the symptoms remitted and she returned to normal life. Pregabalin was effective in treating these JFM patients when used in combination with supplementary physical and psychological therapy. However, the use of pregabalin has yet to be firmly established, and multicenter studies are required to corroborate its efficacy in treating the disease.
