Abstract
Paroxysmal hemicrania is a rare disease characterized by complete response to indomethacin. We report three patients with paroxysmal hemicrania. Case 1: A 31-year-old male experienced frequent right occipital pain accompanied by ipsilateral lacrimation, blepharoptosis, and nasal congestion. Indomethacin administration was started, resulting in complete resolution of the pain. Case 2: A 63-year-old female had been treated for cluster headaches with prednisolone, lithium carbonate, and verapamil, but had shown progressive shortening of the remission periods. Since pain was alleviated by the administration of diclofenac during attacks, regular administration of indomethacin was started, which resulted in the disappearance of these attacks. Case 3: A 77-year-old male had been treated for trigeminal neuralgia with carbamazepine. As ipsilateral lacrimation, blepharoptosis, and conjunctival congestion occasionally occurred during attacks, indomethacin was administered adjunctively. Subsequently, pain tapered and disappeared. Craniofacial pain often requires long-term treatment, but the concurrence of other disorders must be considered if the nature of the pain changes during the course or if it is refractory to treatment.
