Abstract
Two cases of patients with difficult pain relief in oral cavity, especially in tongue and palate were treated. Both case 1 and 2 had shown primarily organized disease in oral cavity and each disease considered to have the trigger of these pain disorders. There was, however, no obvious clinical changes in their oral cavities at our first examination. We performed the treatments of stellate ganglion block at the pain-dependent side and administration of psychoactive agents such as fluphenazine, amitriptyline and lorazepam. This combination therapy was successfully effective for these pain, although the pain was recured when this therapy was interrupted. Since when the treatments were restarted the prominent pain relief was obtained, this pain clinic has been continuing up to now for 20 months in case 1 and 9 months in case 2, respectively. Pain disorder in oral cavity called glossodynia involved several parts of psychosomatic diseases, and stellate ganglion block therapy accompanied with psychoactive agents might be effective for this type of pain disorders.