Abstract
While palliative radiation therapy is well-known to be one of the most useful therapy for cancer pain due to spinal-epidural metastasis, the radiation therapy is sometimes difficult to fulfill because of the intractable cancer pain per se. We experienced two cases with intractable cancer pain due to bone metastasis. When these cases were hard to start palliative radiation therapy because of the intractable pain, we treated with continuous intrathecal administration of lidocaine and morphine during the palliative radiation therapy. Excellent pain relief was obtained in all patients during and after the radiation therapy. Palliative radiation therapy combined with continuous subarachnoid analgesia is thought to be a useful therapy for the intractable cancer pain due to spinal-epidural metastasis.