Abstract
Blepharospasm is characterized by dystonic movement of periorbital muscles with unknown etiology, and the treatment of this condition has been disappointing. Since botulinum toxin injection was commenced in 1997, a great advancement has been seen in the management of this disease. The fact that blepharospasm is a complicated neural disorder, which often is associated with dystonia of multiple facial muscles and with psychiatric change, mere relaxation of periorbital muscles dose not always lead to successful treatment. Still, botulinum toxin is the best agent ever existed in the treatment of blepharospasm.
