Abstract
Repeated applications of Stellate Ganglion Block (SGB) are known to improve symptoms of allergic rhinitis but the mechanism of the effects is not clear. Correlation between sympathetic nervous system and pain, and or immune system has been reported. To examine if the blockade of the part of sympathetic nervous system like SGB could affect pain threshold and immune system activity of whole body. Four weeks after the operation Tail Flick test was examined. YAC1 cell lytic activities of the splenic natural killer cell (NK activity) between sham operation group and cervical sympathetic denervation group also were compared. Pain threshold was no change between two groups. But, NK activity of denervation group was significantly lower than that of sham group. The result suggests the possibility of manipulation of immune activity of individuals by partial blockade of sympathetic nervous system.
