Study of Solidified Enteral and Oral Nutritional Formula on Transformation and Transit in Digestive Tract-Fundamental Experiments in Rats-

Abstract

Enteral nutrition, which was solidified by pectin, was studied in rats. Namely, solidified enteral nutrition dissolution in simulated digestive fluids, transit effects, the occurrence of gastroesophageal reflux and fecal status were monitored.
In comparison with nutrition solidified by agar or gelatin, the nutrition solidified by pectin maintained its solidity in simulated gastric juices, but quickly dissolved in simulated intestinal juices. In comparison with liquid forms of nutrition, solidified nutrition exhibited prolonged gastric emptying time, while no difference in intestinal transit was observed. Solidified nutrition significantly reduced the occurrence of gastroesophageal reflux and the incidence of diarrhea in rats.